Kraus W
Z Gesamte Inn Med. 1982 Feb 1;37(3):91-3.
Quantitative and qualitative investigations of the erythropoiesis in the sternal marrow of untreated 52 patients with a plasmacytoma and 46 patients with a chronic lymphatic leukaemia resulted in about half the cases in an indicated or more distinct megaloblastic disturbance of maturation in a part of the erythroblasts. These changes of the erythroblastic cells might be the expression of a neoplastic transformation and of a disturbance of the differentiation of the pluripotent stem cells in these diseases.
对52例未经治疗的浆细胞瘤患者和46例慢性淋巴细胞白血病患者胸骨骨髓中的红细胞生成进行定量和定性研究,结果发现约半数病例的部分成红细胞存在明显或更显著的巨幼细胞成熟障碍。这些成红细胞的变化可能是这些疾病中肿瘤转化以及多能干细胞分化紊乱的表现。