Belyĭ V P, Vorob'ev V S, Zakharov N D
Zh Evol Biokhim Fiziol. 1982 Mar-Apr;18(2):161-4.
On the whole brain of rabbits and surviving slices of the hippocamp of mice, studies have been made of the sensitivity and peculiarities of the reaction of hippocampal neurones to hydrocortison administration. In experiments on whole animals, the drug was applied to the hippocampal neurones by means of microionophoretic technique. In experiments with slices, the steroid hormone was injected with a special micropipette directly in to the chamber with the slice. It was shown that there are many nervous cells in the hippocamp which are sensitive to corticosteroids. Possible role of steroid hormones in neurochemical mechanisms of the hippocamp is discussed.
在兔子的全脑以及小鼠海马体的存活切片上，对海马体神经元对氢化可的松给药反应的敏感性和特性进行了研究。在对完整动物的实验中，通过微离子电泳技术将药物施加于海马体神经元。在切片实验中，使用特殊的微量移液器将类固醇激素直接注射到装有切片的腔室中。结果表明，海马体中有许多对皮质类固醇敏感的神经细胞。文中讨论了类固醇激素在海马体神经化学机制中的可能作用。
