Krasil'nikov A P, Zmushko L S, Adarchenko A A
Zh Mikrobiol Epidemiol Immunobiol. 1982 Apr(4):26-30.
The comparative study of 830 hospital and 181 extrahospital S. aureus strains has revealed the existance of the interpopulation (group, geographic) variability of this species. Hospital strains differ from those inhabiting other places by the composition of phago- and resistovars, greater resistance to antibiotics, antiseptic and disinfecting agents, the inhibiting action of antagonist, as well as by pronounced antagonistic activity. The biological characteristics of such strains allow one to classify them with the hospital ecological variants (ecovars) of S. aureus. These properties of hospital strains give them selective advantages in hospitals over extrahospital strains, and the latter are thus ousted from the skin surface, mucous membranes, wound surfaces. The measures taken to prevent hospital infections must be aimed mainly against the hospital ecovars of these bacteria.
对830株医院内金黄色葡萄球菌菌株和181株医院外金黄色葡萄球菌菌株的比较研究揭示了该物种在群体间（组、地理）的变异性。医院菌株与其他地方的菌株在吞噬型和耐药型的组成、对抗生素、防腐剂和消毒剂的更强耐药性、拮抗剂的抑制作用以及明显的拮抗活性方面存在差异。这些菌株的生物学特性使其可被归类为金黄色葡萄球菌的医院生态变体（生态型）。医院菌株的这些特性使其在医院环境中比医院外菌株具有选择优势，从而将后者从皮肤表面、粘膜、伤口表面排挤出去。预防医院感染所采取的措施必须主要针对这些细菌的医院生态型。
