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人类早粗线期和中/晚期粗线期精母细胞的完整常染色体染色粒图谱。

Complete autosomal chromomere maps of human early and mid/late pachytene spermatocytes.

作者信息

Jagiello G M, Fang J S

出版信息

Am J Hum Genet. 1982 Jan;34(1):112-24.

Abstract

Specific identification of each bivalent of human spermatocytes at early and mid/late pachytene was obtained from chromomere maps developed by analyzing complete, well-spread cells from five subjects aged 31-49. The total number of chromomeres on the early autosomal bivalents was 499 and 386 at the mid/late stage. Regional analysis revealed more chromomeres at early pachytene than at mid/late, with 12 exceptions having equal numbers. Correspondence of chromomeres with mitotic prometaphase G-bands was found in all bivalents. Four chromomeres were found in region 1 of the 9q at early pachytene and two at mid/late. Differences between the map for chromosome no. 10 observed in this study and others were noted.

摘要

通过分析5名年龄在31至49岁受试者的完整、铺展良好的细胞所绘制的染色粒图谱,实现了对人类初级精母细胞早期和粗线期中/后期各二价体的特异性识别。常染色体二价体在早期的染色粒总数为499个,在中/后期为386个。区域分析显示,粗线期早期的染色粒比中/后期更多,有12个例外情况数量相等。在所有二价体中均发现染色粒与有丝分裂前中期G带相对应。在粗线期早期,9号染色体q臂1区发现4个染色粒,在中/后期发现2个。本研究中观察到的10号染色体图谱与其他图谱之间存在差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1497/1685207/1c7365076246/ajhg00355-0115-a.jpg

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