Portes Silva J M, Parás Chavero E, Martińez Sánchez E, Hervella Pérez L
Arch Inst Cardiol Mex. 1978 Sep-Oct;48(5):1026-39.
During five years or until death, we had under observation 74 patients who survived the acute phase of myocardial infarction, 66 patients with angor inestable, and a third group, also of 66 patients of the coronary unit, but whose cases didn't show evidence of their illness being due to myocardial infarction. The general features were similar in the three groups. The patients outliving myocardial infarction reached 69%; those surviving angor inestable, reached 79%, and the survivors of the no-coronary group, 92.5%. There were not significant differences among the three groups in mortality rate due to non cardial illnesses. The differences are in relation with sudden death; in the first groups, 14.8%, 10.6% in the second group, and only 1.5% in the third one. In the coronary groups half the total mortality was due to sudden death. Death was instantaneous in 26% of the cases and 52% occurred in less than two hours. All of these sudden deaths occurred out of the Hospital. Patients with antecedents of previous myocardial infarction showed from 3 to 6 more sudden deaths than those patients suffering a first myocardial infarction. The myocardial infarction patients who developed cardiomegaly afterwards registered two and a half more sudden deaths than those without cardiomegaly. Differences were highly significant; 28.5% sudden deaths in those patients with cardiomegaly and 8.4% in patients without cardiomegaly. These results show that the higher rate of sudden deaths is due to a more extensive myocardial damage. Arterial hypertension also constitutes and important risk of sudden death, even when it is properly controlled after the acute period.
在五年期间或直至死亡,我们观察了74例度过心肌梗死急性期的患者、66例不稳定型心绞痛患者,以及第三组同样66例冠心病监护病房的患者,但其病例未显示有因心肌梗死致病的证据。三组的一般特征相似。度过心肌梗死的患者存活率达69%;不稳定型心绞痛存活者达79%,非冠心病组存活者达92.5%。三组因非心脏疾病导致的死亡率无显著差异。差异在于猝死方面;第一组为14.8%,第二组为10.6%,第三组仅为1.5%。在冠心病组,总死亡率的一半归因于猝死。26%的病例猝死瞬间发生,52%在两小时内发生。所有这些猝死均发生在院外。有既往心肌梗死病史的患者比首次发生心肌梗死的患者猝死多3至6例。之后出现心脏扩大的心肌梗死患者比未出现心脏扩大的患者猝死多2.5倍。差异非常显著;心脏扩大患者的猝死率为28.5%,未出现心脏扩大患者的猝死率为8.4%。这些结果表明,较高的猝死率是由于更广泛的心肌损伤。即使在急性期后得到适当控制,动脉高血压也构成猝死的重要风险。