精子（仓鼠卵）穿透试验在不育夫妇评估中的益处。

Benefits of the sperm (hamster ova) penetration assay in the evaluation of the infertile couple.

作者信息

Stenchever M A, Spadoni L R, Smith W D, Karp L E, Shy K K, Moore D E, Berger R

出版信息

Am J Obstet Gynecol. 1982 May 1;143(1):91-6. doi: 10.1016/0002-9378(82)90688-3.

Abstract

The males of 310 infertile couples and 30 control couples (current pregnancy) were evaluated with the sperm (hamster ova) penetration assay (SPA) and seminal fluid analysis (SFA). The SPA was found to have a sensitivity of 100% and a specificity of 97% compared to 41% and 90%, respectively, for the SFA. The highest degree of concordance of the two tests existed when both tests were abnormal and no female factor was identified. The poorest concordance occurred when the SFA was normal and no female infertility factor was identified. In almost all cases of unexplained infertility where no female infertility factor was present, the problem could be assigned to the man, as evidenced by an abnormal SPA. The SFA seemed to have some predictive value with respect to the outcome following treatment of the man.

摘要

对310对不育夫妇及30对对照夫妇（目前已怀孕）的男性进行了精子（仓鼠卵）穿透试验（SPA）和精液分析（SFA）。结果发现，与SFA的敏感性41%和特异性90%相比，SPA的敏感性为100%，特异性为97%。当两项检测均异常且未发现女性因素时，两项检测的一致性程度最高。当SFA正常且未发现女性不育因素时，一致性最差。在几乎所有无女性不育因素的不明原因不育病例中，问题都可归因于男性，这一点可通过异常的SPA得到证明。SFA似乎对男性治疗后的结果具有一定的预测价值。