Frontera-Izquierdo P, Unceta Aguirre L, Cabezuelo Huerta G, Vázquez Pérez J
An Esp Pediatr. 1982 Jan;16(1):23-7.
Growth status was studied in 48 children with simple and severe ventricular septal defect successfully repaired. The average follow-up post surgery was 3.5 years (range, two-seven years). Children with birth weight less of 2,500 g. and extracardiac anomalies or chromosomal syndromes were excluded. Measurements before surgical treatment revealed height and weight status to be subnormal and related to physiological severity. However lowest weight score was found in youngest patients and height score are uniformly affected in both group ages. Surgical repair resulted in significant weight gain in all groups. Final height in the youngest age groups is near normal levels. However in the group of children repaired after age of two years the changes in height were not statistically significant. No change in the subnormal growth pattern was noted in five children (10.4%). Surgery of large and severe ventricular septal defect in very early infancy offers the best prospect for growth.
对48例成功修复单纯性和重度室间隔缺损的儿童的生长状况进行了研究。术后平均随访3.5年（范围为2至7年）。出生体重低于2500克、有心脏外异常或染色体综合征的儿童被排除在外。手术治疗前的测量显示身高和体重状况低于正常水平，且与生理严重程度相关。然而，最年轻患者的体重得分最低，两个年龄组的身高得分均受到一致影响。手术修复使所有组的体重显著增加。最年轻年龄组的最终身高接近正常水平。然而，在两岁后接受修复的儿童组中，身高变化无统计学意义。5名儿童（10.4%）的生长模式低于正常水平未见变化。在婴儿早期对大型和重度室间隔缺损进行手术，为生长提供了最佳前景。
