Kaidbey K H, Witkowski T A, Kligman A M
Arch Dermatol. 1982 May;118(5):315-8.
Because heat has been reported to influence adversely short- and long-term ultraviolet (UV)-radiation-induced skin damage in animals, we investigated the short-term effects of infrared radiation on sunburn and on phototoxic reactions to topical methoxsalen and anthracene in human volunteers. Prior heating of the skin caused suppression of the phototoxic response to methoxsalen as evidenced by an increase in the threshold erythema dose. Heat administered either before or after exposure to UV radiation had no detectable influence on sunburn erythema or on phototoxic reactions provoked by anthracene.
由于据报道热会对动物短期和长期紫外线(UV)辐射引起的皮肤损伤产生不利影响,我们研究了红外线辐射对人体志愿者晒伤以及对局部甲氧沙林和蒽的光毒性反应的短期影响。皮肤预先加热导致对甲氧沙林的光毒性反应受到抑制,这表现为红斑阈值剂量增加。在紫外线辐射暴露之前或之后给予热,对晒伤红斑或蒽引发的光毒性反应均未检测到影响。