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大网膜:其作为带血管游离移植物用于头颈部重建的应用

The omentum: its use as a free vascularized graft for reconstruction of the head and neck.

作者信息

Jurkiewicz M J, Nahai F

出版信息

Ann Surg. 1982 Jun;195(6):756-65. doi: 10.1097/00000658-198206000-00012.

Abstract

The experience at Emory University Affiliated Hospitals with transplantation of the greater omentum as a free revascularized graft in 18 patients is presented. In each instance, there was realization of the therapeutic objective, either 1) the amelioration of congenital or acquired somatic deformity (14 patients) or 2) the control of infection (4 patients). Because the omentum is a syncytium of blood vessels and a variable amount of fat within redundant leaves of peritoneal membrane laden with macrophages, it is a tissue that serves admirably its extended role as an extracelomic free transplant. The greater omentum has been used for this purpose in five patients with hemifacial atrophy (Romberg's disease); three patients with hemifacial microsomia (first and second branchial arch syndrome); two patients with extensive losses of the maxilla, palate, and face due to a shotgun blast; two patients with atrophy and facial growth arrest due to x-irradiation; and two patients with deformity of the jaw and neck following tumor resection. In three additional patients, the omentum was used to obliterate the dead space after debridement of an infected open frontal sinus following failure of conventional therapy. In one instance, a revascularized free graft of omentum was used to salvage a patient with an exposed irradiated carotid artery graft and skin flap failure following radical neck dissection. In these 18 patients, there were no intra-abdominal complications consequent to harvest of the omentum. In one patient afflicted with hemifacial atrophy, there was spotty necrosis of the overlying attenuated facial skin flap and limited fat necrosis. In the follow-up period of four months to seven years, there has been no instance of late resorption. The method is reliable and has considerable promise in reconstructive surgery.

摘要

本文介绍了埃默里大学附属医院对18例患者进行游离带血管大网膜移植的经验。在每例患者中,均实现了治疗目标,即:1)改善先天性或后天性躯体畸形(14例患者);2)控制感染(4例患者)。由于大网膜是血管的合体,在充满巨噬细胞的腹膜多余叶内含有数量不等的脂肪,因此它作为一种体腔外游离移植组织,能出色地发挥其扩展作用。大网膜已被用于治疗5例半侧面部萎缩(Romberg病)患者;3例半侧颜面短小畸形(第一和第二鳃弓综合征)患者;2例因猎枪伤导致上颌骨、腭部和面部广泛缺损的患者;2例因X线照射导致萎缩和面部生长停滞的患者;以及2例肿瘤切除后颌骨和颈部畸形的患者。另外3例患者在常规治疗失败后,使用大网膜填充感染性开放额窦清创后的死腔。有1例患者在根治性颈清扫术后,使用带血管游离大网膜移植挽救了1例暴露的放疗后颈动脉移植和皮瓣坏死的患者。在这18例患者中,摘取大网膜后未出现腹腔内并发症。1例半侧面部萎缩患者,其覆盖的变薄面部皮瓣出现散在坏死,脂肪坏死局限。在4个月至7年的随访期内,未出现晚期吸收的情况。该方法可靠,在重建手术中有很大的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3906/1352675/cb2ed422bb2c/annsurg00148-0090-a.jpg

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