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慢性代谢性酸中毒对犬体内肝脏和肌肉谷氨酰胺代谢的影响。

The effects of chronic metabolic acidosis on liver and muscle glutamine metabolism in the dog in vivo.

作者信息

Fine A

出版信息

Biochem J. 1982 Jan 15;202(1):271-3. doi: 10.1042/bj2020271.

DOI:10.1042/bj2020271
PMID:7082312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1158103/
Abstract
  1. Chronic HCl acidosis was induced in dogs. 2. Hepatic extraction of glutamine fell compared with normal animals. 3. Muscle glutamine production was unchanged in acidosis. 4. The results are discussed in relation to inter-organ glutamine metabolism in acidosis in vivo.
摘要
  1. 在犬类中诱发慢性盐酸酸中毒。2. 与正常动物相比，肝脏对谷氨酰胺的摄取量下降。3. 酸中毒时肌肉中谷氨酰胺的生成量未发生变化。4. 结合体内酸中毒时器官间谷氨酰胺代谢对结果进行了讨论。

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1
The effects of chronic metabolic acidosis on liver and muscle glutamine metabolism in the dog in vivo.慢性代谢性酸中毒对犬体内肝脏和肌肉谷氨酰胺代谢的影响。
Biochem J. 1982 Jan 15;202(1):271-3. doi: 10.1042/bj2020271.
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本文引用的文献

1
RENAL PRODUCTION AND EXCRETION OF AMMONIA.肾脏对氨的生成与排泄
Am J Med. 1964 May;36:720-42. doi: 10.1016/0002-9343(64)90182-2.
2
Glutamine release from hindlimb and uptake by kidney in the acutely acidotic rat.急性酸中毒大鼠后肢谷氨酰胺的释放及肾脏对其的摄取
Biochem J. 1980 May 15;188(2):557-60. doi: 10.1042/bj1880557.
3
Interorgan relationships for glutamine metabolism in normal and acidotic rats.正常和酸中毒大鼠体内谷氨酰胺代谢的器官间关系
Am J Physiol. 1981 May;240(5):E519-25. doi: 10.1152/ajpendo.1981.240.5.E519.
4
Studies on the transport of glutamate in Ehrlich cells--inhibition by other amino acids and stimulation by H-ions.艾氏腹水癌细胞中谷氨酸转运的研究——其他氨基酸的抑制作用及氢离子的刺激作用。
Biochem Z. 1965 Sep 30;342(5):542-52.
5
The effect of perfusate pH on glutamine metabolism in the isolated perfused rat liver.灌注液pH值对离体灌注大鼠肝脏谷氨酰胺代谢的影响。
J Biol Chem. 1970 Oct 25;245(20):5491-7.
6
Metabolism of glutamine by the intact functioning kidney of the dog. Studies in metabolic acidosis and alkalosis.犬完整功能肾脏对谷氨酰胺的代谢。代谢性酸中毒和碱中毒的研究。
J Clin Invest. 1972 Mar;51(3):557-65. doi: 10.1172/JCI106844.
7
The formation of glutamine and alanine in skeletal muscle.骨骼肌中谷氨酰胺和丙氨酸的形成。
J Biol Chem. 1974 Sep 10;249(17):5500-6.
8
Identification of ketone bodies and glutamine as the major respiratory fuels in vivo for postabsorptive rat small intestine.确定酮体和谷氨酰胺是禁食大鼠小肠在体内的主要呼吸燃料。
J Biol Chem. 1978 Jan 10;253(1):69-76.
9
A role for bicarbonate in the regulation of mammalian glutamine metabolism.碳酸氢盐在哺乳动物谷氨酰胺代谢调节中的作用。
Biochem J. 1979 Dec 15;184(3):599-606. doi: 10.1042/bj1840599.