Willcourt R J, Paust J C, Queenan J T
Br J Anaesth. 1982 Jun;54(6):635-41. doi: 10.1093/bja/54.6.635.
Forty-six of 64 high risk labours were managed with continuous lumbar extradural analgesia. Fetal heart rate (FHR) and continuous transcutaneous PO2 (tcPO2) measurements were made in the 64 patients. Abnormal fetal heart rate patterns and low tcPO2 values associated with the onset of the extradural block were noted in 9% of these cases. A decrease in maternal arterial pressure and uterine hypertonus appeared to be responsible, singly or in combination, for the changes. These effects and the changes in FHR were not seen in the 18 mothers not receiving extradural analgesia. The supine position was associated with slightly smaller fetal tcPO2 values than the preferred lateral positions, with a significant worsening of the fetal tcPO2 values after induction of the extradural block although, overall, extradural analgesia neither improved nor impaired the fetal tcPO2.
64例高危分娩中有46例采用持续腰段硬膜外镇痛进行处理。对这64例患者进行了胎儿心率(FHR)和经皮氧分压(tcPO2)的持续监测。在这些病例中,9%出现了与硬膜外阻滞开始相关的异常胎儿心率模式和低tcPO2值。产妇动脉压下降和子宫张力过高单独或共同作用似乎是导致这些变化的原因。在未接受硬膜外镇痛的18名产妇中未观察到这些影响以及FHR的变化。仰卧位时胎儿tcPO2值略低于首选的侧卧位,硬膜外阻滞诱导后胎儿tcPO2值显著恶化,不过总体而言,硬膜外镇痛既未改善也未损害胎儿tcPO2。