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[暴露于低强度非电离微波辐射下脑和肝脏的超微细胞化学变化]

[Ultracytochemical changes in the brain and liver in exposure to low-intensity nonionizing microwave radiation].

作者信息

Belokrinitskiĭ V S, Tomashevskaia L A, Konobeeva G I

出版信息

Biull Eksp Biol Med. 1982 Apr;93(4):112-6.

PMID:7082790
Abstract

The morphological (including electron microscopy, histochemistry, morphometry) and biochemical methods were used in experiments on 478 white rats to determine the content of glycogen, tigroid substance, RNA, DNA and activity of the enzymes (SDH, MDH, LDH, G-6-PDH, phosphorylase) in intact animals after and during exposure to nonionizing microwave radiation (NMR), 30 and 60 days after the rehabilitation period, as well as after physiological exposures (hypoxia and NMR of higher intensity). It was disclosed that repeated exposure to little doses of NMR alters the structural and functional bases of the mechanisms that regulate cell metabolism, produces conformational changes in the chemical substances and thus exerts a damaging action on the delicate cell structures; redistributes the action on the pathways of energy formation at the expense of compensatory protein synthesis and the increase enzymatic systems; increases the resistance to hypoxia and action of NMR of higher intensities.

摘要

采用形态学(包括电子显微镜、组织化学、形态计量学)和生物化学方法,对478只白鼠进行实验,以测定完整动物在暴露于非电离微波辐射(NMR)期间及之后、康复期30天和60天后,以及在生理暴露(缺氧和更高强度的NMR)后糖原、虎斑物质、RNA、DNA的含量和酶(SDH、MDH、LDH、G-6-PDH、磷酸化酶)的活性。结果表明,反复暴露于小剂量的NMR会改变调节细胞代谢机制的结构和功能基础,使化学物质发生构象变化,从而对脆弱的细胞结构产生破坏作用;以补偿性蛋白质合成和酶系统增加为代价,重新分配对能量形成途径的作用;增加对缺氧和更高强度NMR作用的抵抗力。

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