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[失血性休克大鼠大脑皮质的微循环与氧张力]

[Microcirculation and oxygen tension in the cerebral cortex of rats with hemorrhagic shock].

作者信息

Udovichenko V I, Shtykhno Iu M

出版信息

Biull Eksp Biol Med. 1982 Apr;93(4):8-9.

PMID:7082809
Abstract

Microcirculatory disturbances in pia mater are followed by change in oxygen tension in the brain cortex. Immediately after bleeding initial decrease of oxygen tension by 60-70% of the basal level was observed. This decrease was induced by initial vasoconstriction and brain cortex hypoxia. After compensation of blood circulation supervened and the cortical blood flow was set to a lower level (30-40 minutes after the decrease), there occurred a phase of oxygen level stabilization. The oxygen tension remained unchanged for a long time and decreased very slowly. More rapid fall of oxygen tension was noticed only at the end of the fourth hour when circulation decompensation set in.

摘要

软脑膜的微循环紊乱会导致大脑皮层氧张力的变化。出血后立即观察到氧张力初始下降,降至基础水平的60 - 70%。这种下降是由初始血管收缩和大脑皮层缺氧引起的。血液循环代偿后(氧张力下降后30 - 40分钟),出现了氧水平稳定期。氧张力长时间保持不变,下降非常缓慢。仅在第四小时末循环失代偿开始时,才注意到氧张力下降得更快。

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