Turina M T, Bosio R, Senning A
Artif Organs. 1978 Aug;2(3):273-6. doi: 10.1111/j.1525-1594.1978.tb03465.x.
A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial heart has been used in four patients with refractory postoperative heart failure not responding to volume loading, pH and electrolyte correction, catecholamines and intra-aortic balloon pumping. Large cannulae were placed in the atria and great vessels. The ventricles were fixed on the chest paracorporeally. The assist system was used as a left heart bypass in one patient and as a biventricular bypass in three other patients. After 48-72 hours, the ventricular function recovered in three patients, permitting removal of the artificial heart. One patient died of cerebral complications six weeks later; the other two recovered completely and were released in good condition. Profound postoperative heart failure can be completely reversed by the use of the paracorporeal artificial heart; the advantage of the system lies in the simplicity of its implantation and removal.
一种带有管状硅橡胶膜和盘形瓣膜的气动人工心脏被用于体外模式下的功能性心脏置换。一种流体驱动系统可调节心率、正负压力以及收缩期/舒张期比率。自1977年8月以来，该人工心脏已应用于4例难治性术后心力衰竭患者，这些患者对容量负荷、pH值和电解质纠正、儿茶酚胺以及主动脉内球囊反搏均无反应。大套管被置于心房和大血管中。心室被体外固定在胸部。辅助系统在1例患者中用作左心旁路，在另外3例患者中用作双心室旁路。48至72小时后，3例患者的心室功能恢复，从而可以移除人工心脏。1例患者六周后死于脑部并发症；另外2例完全康复并状况良好地出院。使用体外人工心脏可使严重的术后心力衰竭完全逆转；该系统的优点在于其植入和移除的简便性。
