Avaria M, Basu P K, Jankie R
Can J Ophthalmol. 1982 Feb;17(1):21-3.
Bioassays performed by the disc diffusion technique on samples of blood, tears, aqueous humour and cornea from 30 rabbits killed 4 to 24 hours following a single intravenous injection of benzylpenicillin (40 mg/kg) showed that the penicillin content of these fluids and tissues progressively decreased with time. However, even after 24 hours the agent could be detected in the samples. The peripheral and central cornea contained similar amounts of penicillin up to 16 hours; thereafter, the peripheral cornea contained more of the agent.
在30只兔子单次静脉注射苄青霉素（40毫克/千克）后4至24小时处死，采用纸片扩散法对其血液、眼泪、房水和角膜样本进行生物测定，结果显示这些体液和组织中的青霉素含量随时间逐渐降低。然而，即使在24小时后，仍能在样本中检测到该药物。直至16小时，周边角膜和中央角膜所含青霉素量相似；此后，周边角膜所含该药物更多。
