足月胎盘培养物中人胎盘催乳素（hPL）的合成与分泌

The synthesis and secretion of human placental lactogen (hPL) in cultured term placenta.

作者信息

Weinstein D, Galski H, Schenker J G, Lorberboum H, de Groot N, Ilan J, Folman R, Hochberg A A

出版信息

Mol Cell Endocrinol. 1982 Apr;26(1-2):189-99. doi: 10.1016/0303-7207(82)90016-8.

Abstract

We studied the in vitro synthesis and secretion of hPL by human term placental tissue incubated in organ culture. Placental tissue maintains a constant pool of hPL. The synthesis of hPL may be the driving force for its secretion. The de novo synthesis and secretion rates of hPL were also investigated. The higher specific radioactivities of the secreted hPL than those found in the tissue may suggest that newly synthesized hPL is preferentially released. The intracellular distribution of hPL was also compared.

摘要

我们研究了在器官培养中培养的足月人胎盘组织中hPL的体外合成与分泌。胎盘组织维持着hPL的恒定储备。hPL的合成可能是其分泌的驱动力。我们还研究了hPL的从头合成和分泌速率。分泌的hPL比组织中的具有更高的比放射性，这可能表明新合成的hPL优先被释放。我们还比较了hPL的细胞内分布。