Fabris F, Casonato A, Randi M L, Varotto L, Scandellari C, Girolami A
Haemostasis. 1982;11(2):102-8. doi: 10.1159/000214648.
We studied platelet survival in 14 cardiac before heart valve replacement using 75Se-methionine 'cohort label'. The temporal variation of plasma and platelet activity was plotted by a continuous curve by means of a computerized interaction of the single points. Then we computed the plasmatic radioactivity fraction used daily for thrombopoiesis and made a subtraction of this aliquot from a experimental activity in the catabolic phase of the slope. Platelet life span obtained after this 'correction' is comparable with the values of random label using 51Cr.
我们使用75Se-蛋氨酸“群组标记”研究了14例心脏瓣膜置换术前患者的血小板存活情况。通过计算机对单点的交互作用，将血浆和血小板活性的时间变化绘制成连续曲线。然后我们计算了每日用于血小板生成的血浆放射性分数，并从斜率分解代谢阶段的实验活性中减去该等分试样。经过这种“校正”后获得的血小板寿命与使用51Cr随机标记的值相当。
