Klausen K, Secher N H, Clausen J P, Hartling O, Trap-Jensen J
J Appl Physiol Respir Environ Exerc Physiol. 1982 Apr;52(4):976-83. doi: 10.1152/jappl.1982.52.4.976.
Six young healthy male subjects performed submaximal and maximal exercise on bicycle ergometers with one leg and two legs before and after 8 wk of one-leg training with each of both legs. The following variables were measured during one- and two-leg exercise: oxygen uptake, heart rate, mean arterial blood pressure, cardiac output, leg blood flow, and iliac arteriovenous differences for oxygen and lactate. After training the maximal oxygen uptake during one- and two-leg exercise was increased by 19 and 11%, respectively. The corresponding cardiac outputs increased by 16 and 11%, respectively. During submaximal one-leg exercise, heart rate decreased by 11%, whereas a decrease of only 2% was seen during submaximal two-leg exercise. Mean blood pressure decreased by about 10 Torr in both types of exercise and during both submaximal and maximal exercise. Maximal leg blood flow increased only by 1.2 l/min during one-leg exercise. Leg blood flow and leg oxygen uptake were smaller during two-leg exercise than during one-leg exercise and more so after training. These findings indicate that one-leg exercise, compared with two-leg exercise, involves circulatory adaptations that respond differently to one-leg training. The findings further imply that oxygen supply to one large muscle group of exercising muscles may be limited by vasoconstriction when another large group of muscles is exercising simultaneously.
六名年轻健康男性受试者在双腿分别进行为期8周的单腿训练前后，使用自行车测力计进行单腿和双腿的次最大强度及最大强度运动。在单腿和双腿运动过程中测量了以下变量：摄氧量、心率、平均动脉血压、心输出量、腿部血流量以及髂动脉血氧和乳酸动静脉差值。训练后，单腿和双腿运动时的最大摄氧量分别增加了19%和11%。相应的心输出量分别增加了16%和11%。在次最大强度单腿运动时，心率下降了11%，而在次最大强度双腿运动时仅下降了2%。在两种运动类型以及次最大强度和最大强度运动期间，平均血压均下降了约10托。单腿运动时最大腿部血流量仅增加了1.2升/分钟。双腿运动时的腿部血流量和腿部摄氧量比单腿运动时小，训练后更是如此。这些发现表明，与双腿运动相比，单腿运动涉及的循环适应对单腿训练的反应不同。这些发现进一步表明，当另一大组肌肉同时运动时，向一组正在运动的大肌肉群的氧气供应可能会受到血管收缩的限制。
