Burr M L, Gray S J, Howells C H
J Hyg (Lond). 1982 Jun;88(3):425-31. doi: 10.1017/s0022172400070285.
Nasal swabs were taken from 369 four-year-old children in two South Wales towns and cultured for Streptococcus pneumoniae. The organism was isolated in 34% of the specimens, similar rates being found in boys and girls in the two towns. The children were swabbed again a year later, when the prevalence of nasal pneumococci had fallen to 25%. There was no association between the presence of the organism on the two occasions. Types 6 and 23 were most often isolated. After excluding children who had received an antibiotic, the proportion carrying a pneumococcus was higher in those who had recently had a respiratory infection than in the rest, although the difference was not quite statistically significant. There was a significant negative association between the presence of Staphylococcus aureus and Strep. pneumoniae.
在南威尔士的两个城镇,从369名4岁儿童中采集了鼻拭子,用于培养肺炎链球菌。在34%的标本中分离出了该病菌,两个城镇的男孩和女孩的检出率相似。一年后再次对这些儿童进行鼻拭子采样,此时鼻腔肺炎球菌的携带率已降至25%。两次采样时该病菌的携带情况之间没有关联。最常分离出的是6型和23型。在排除接受过抗生素治疗的儿童后,近期有过呼吸道感染的儿童携带肺炎球菌的比例高于其他儿童,尽管差异在统计学上不太显著。金黄色葡萄球菌的携带情况与肺炎链球菌之间存在显著的负相关。