Houpt J B, Alpert B, Lotem M, Greyson N D, Pritzker K P, Langer F, Gross A E
J Rheumatol. 1982 Jan-Feb;9(1):81-90.
Spontaneous osteonecrosis (ON) of the medial tibial plateau was diagnosed in 15 elderly patients (21 knees). The onset was characterized by sudden severe medial knee pain, usually with an effusion. Radiographic changes suggestive of ON occurred medial to the weight bearing area of the medial tibial plateau in 9 knees and were normal in 12. The disease entity was documented most clearly by intense radionuclide bone uptake in the medial tibial plateau in all knees. It could be distinguished clinically and radiologically from medial femoral ON, tibial stress fractures and primary osteoarthritis (OA). Tibial ON did not appear to accelerate the development or progression of OA of the knee and most patients were better in less than 1 year.
15例老年患者（21个膝关节）被诊断为胫骨内侧平台自发性骨坏死（ON）。发病的特点是膝关节内侧突然出现严重疼痛，通常伴有积液。9个膝关节的X线片显示胫骨内侧平台负重区域内侧有提示ON的改变，12个膝关节的X线片正常。通过所有膝关节胫骨内侧平台放射性核素骨摄取增强，该疾病实体得到了最清晰的记录。它在临床和放射学上可与股骨内侧ON、胫骨应力性骨折和原发性骨关节炎（OA）相鉴别。胫骨ON似乎不会加速膝关节OA的发展或进展，大多数患者在不到1年的时间里病情好转。
