大鼠广州管圆线虫的实验性轻度感染

Experimental light infection of Angiostrongylus cantonensis in rats.

作者信息

Sano M, Ishii A I, Kino H, Hayashi M

出版信息

J Trop Med Hyg. 1982 Apr;85(2):73-5.

Abstract

An experimental infection with a smaller number of Angiostrongylus cantonensis, using rats as hosts, was carried out. When the rats were infected with one and two larvae of A. cantonensis, the infection rates were 45.5% and 73.3% and recovery rates of the adult worms were 45.5% and 66.7%, respectively. In cases when more than three larvae were given to rats, all rats were found to be infected and recovery rates were around 70%, which is the same as in the case of infection with many larvae. The recovered worms were all mature and showed no important difference in their morphological measurements. It was concluded that the larvae of A. cantonensis were able to infect rats in small numbers, and completely develop into adult worms. It is suggested that human infection could occur in the same way.

摘要

以大鼠为宿主，进行了感染少量广州管圆线虫的实验。当大鼠感染1条和2条广州管圆线虫幼虫时，感染率分别为45.5%和73.3%，成虫回收率分别为45.5%和66.7%。当给大鼠接种3条以上幼虫时，所有大鼠均被感染，回收率约为70%，与感染多条幼虫的情况相同。回收的蠕虫均已成熟，其形态测量无显著差异。得出的结论是，广州管圆线虫幼虫能够少量感染大鼠，并完全发育为成虫。提示人类感染可能以同样的方式发生。