Reinstein L E, McShan D, Glicksman A S
Med Phys. 1982 Mar-Apr;9(2):240-9. doi: 10.1118/1.595221.
The validity of conclusions drawn from multi-institutional radiotherapy studies is dependent upon the degree to which participating hospitals adhere to study requirements. A major effort undertaken by the Quality Assurance Review Center (QARC) assesses whether or not patient data which are deemed evaluable actually conform to the radiotherapy requirements of the research protocol. This paper presents the methods and results of this effort which has been ongoing for the past five years. The Dosimetry Review System (DRS) is a set of computer programs which make use of verified radiation beam data to evaluate the daily dose, total dose, dose uniformity, and TDF for protocol treatment. These programs can be adapted to facilitate and document the routine chart-checking procedures at any large radiotherapy department. The DRS data base includes radiotherapy parameters of 600 teletherapy units at more than 250 institutions in the United States and abroad. The design of the data base, the computerized review process, and the calculational algorithms are discussed.
多机构放射治疗研究所得出结论的有效性取决于参与医院遵守研究要求的程度。质量保证审查中心（QARC）所做的一项主要工作是评估被认为可评估的患者数据是否实际符合研究方案的放射治疗要求。本文介绍了过去五年来这项工作的方法和结果。剂量测定审查系统（DRS）是一组计算机程序，利用经过验证的辐射束数据来评估方案治疗的每日剂量、总剂量、剂量均匀性和总剂量因子（TDF）。这些程序可进行调整，以方便和记录任何大型放射治疗科室的常规图表检查程序。DRS数据库包含美国和国外250多家机构的600个远距离治疗设备的放射治疗参数。文中讨论了数据库的设计、计算机化审查过程和计算算法。
