Pabo C O, Krovatin W, Jeffrey A, Sauer R T
Nature. 1982 Jul 29;298(5873):441-3. doi: 10.1038/298441a0.
From differences in the ability of fragments of the lambda repressor to protect operator bases from chemical modification we suggest that the first few N-terminal residues of the lambda repressor form an extended arm that reaches around the back of the DNA helix when repressor binds to the operator.
从λ阻遏物片段保护操纵基因碱基免受化学修饰的能力差异,我们推测,当阻遏物与操纵基因结合时,λ阻遏物N端的前几个残基形成一个延伸臂,该延伸臂环绕在DNA螺旋的背面。