Pogorelyĭ V E, Gaevyĭ M D
Biull Eksp Biol Med. 1978 Oct;86(10):438-41.
It was established in acute experiments on anesthetised and nonanesthetised cats by means of resistography that methylapogalanthamine decreased the total arterial pressure, the tone of cerebral vessels, extracranial and femoral vessels. The effect of the latter was more pronounced. A two-phase reaction (dilatation-constriction) was not rare. Methylapogalanthamine diminished the constriction reaction of intra- and extracranial vessels in response to st mulation of the cervical sympathetic nerves. The vasodilator action of methylapogalanthamine was enhanced by anesthesia and decreased by rausedyl.
通过电阻描记法在麻醉和未麻醉的猫身上进行的急性实验表明，甲基阿扑加兰他敏可降低总动脉压、脑血管、颅外血管和股血管的张力。对股血管的作用更为明显。两相反应（扩张 - 收缩）并不少见。甲基阿扑加兰他敏可减弱颈交感神经刺激引起的颅内和颅外血管的收缩反应。麻醉可增强甲基阿扑加兰他敏的血管舒张作用，而萝芙木碱则可减弱其作用。
