Giordano R, Volpe G, Tambato E, Tavolato B
Riv Neurol. 1982 Jan-Feb;52(1):24-32.
A clinical-pathological study is presented concerning a patient affected by a demential syndrome at a young age (32 years). The neurological examination of the patient disclosed an asymmetry of the deep reflexes and a pale optic disk in both eyes. The pathological examination showed a typical MS, with extensive involvement of the frontal lobes. From our case and from those rarely reported in the literature, it appears that a demential syndrome can rarely be symptomatic of an initial MS. However even in these exceptional cases some neurological signs suggestive of MS are usually present.
本文呈现了一项针对一名年轻（32岁）痴呆综合征患者的临床病理研究。对该患者的神经学检查发现双侧深反射不对称且双眼视盘苍白。病理检查显示为典型的多发性硬化症，额叶广泛受累。从我们的病例以及文献中罕见报道的那些病例来看，似乎痴呆综合征很少会是早期多发性硬化症的症状。然而，即使在这些特殊病例中，通常也会出现一些提示多发性硬化症的神经学体征。
