Mazières B, Rami J, Thiechart M, Arlet J
Rev Rhum Mal Osteoartic. 1982 Mar 25;49(4):263-71.
The authors study the effects of ligation of the infra-renal aorta on the bone marrow in the femoral shafts in ten rabbits, from a histopathological and biochemical standpoint. Histology revealed marrow necrosis in nine cases out of ten. They describe the appearances of this necrosis by light and electron microscopy. In five cases it was focal and partial and in four cases total. It sometimes involved only the haematopoietic tissue, leaving fatty tissue unaffected. The latter would thus seem to be more resistant to ischaemia. Study of lipids showed a decrease in polyunsaturated fatty acids, a decrease which was more marked in the ischaemic femurs than in the humerus of the same rabbits.
作者从组织病理学和生物化学角度研究了十只兔子肾下主动脉结扎对股骨干骨髓的影响。组织学检查显示十只中有九只出现骨髓坏死。他们通过光学显微镜和电子显微镜描述了这种坏死的表现。五例为局灶性和部分性坏死，四例为完全坏死。有时仅累及造血组织，脂肪组织未受影响。因此，脂肪组织似乎对缺血更具抵抗力。脂质研究显示多不饱和脂肪酸减少，这种减少在缺血的股骨中比在同一只兔子的肱骨中更为明显。
