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类风湿关节炎关节渗出液的细胞学。形态学与制片技术。

The cytology of joint exudates in rheumatoid arthritis. Morphology and preparation techniques.

作者信息

Bjelle A, Norberg B, Sjögren G

出版信息

Scand J Rheumatol. 1982;11(2):124-8. doi: 10.3109/03009748209098176.

DOI:10.3109/03009748209098176
PMID:7089502
Abstract

The cytology of joint exudates from patients with rheumatoid arthritis was examined by preparation of air-dried smears; a procedure that involved cytocentrifugation of synovial fluids following dilution in a balanced salt solution containing albumin. This procedure provided a monolayer of homogeneously distributed exudate cells with excellent preservation of morphological details. The dominant cell type in the exudates was polymorphonuclear leukocytes, often with signs of necrobiosis. The small and medium-sized mononuclear cells were lymphocyte-like and vital-looking. The large mononuclear cells displayed signs of extensive phagocytosis, especially phagocytosis of polymorphonuclear leukocytes. It is suggested that the granulocytes of the synovial fluid are cells which have reached their function compartment, where they work and die.

摘要

通过制备空气干燥涂片对类风湿性关节炎患者关节渗出液的细胞学进行了检查;该程序包括在含有白蛋白的平衡盐溶液中稀释后对滑液进行细胞离心。此程序提供了单层均匀分布的渗出细胞,形态细节保存良好。渗出液中的主要细胞类型是多形核白细胞,常伴有细胞坏死迹象。中小单核细胞呈淋巴细胞样且外观有活力。大单核细胞显示出广泛吞噬的迹象,尤其是对多形核白细胞的吞噬。提示滑液中的粒细胞是已到达其功能区室的细胞,它们在那里发挥作用并死亡。

相似文献

1
The cytology of joint exudates in rheumatoid arthritis. Morphology and preparation techniques.类风湿关节炎关节渗出液的细胞学。形态学与制片技术。
Scand J Rheumatol. 1982;11(2):124-8. doi: 10.3109/03009748209098176.
2
Joint fluid leukocytosis of patients with rheumatoid arthritis evidence for neutrophil and monocyte chemotaxis in vivo.类风湿关节炎患者关节液白细胞增多症:体内中性粒细胞和单核细胞趋化性的证据
Clin Rheumatol. 1983 Sep;2(3):237-42. doi: 10.1007/BF02041397.
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[Electron microscope studies of the pannus in rheumatoid arthritis].[类风湿性关节炎中血管翳的电子显微镜研究]
Z Rheumatol. 1974 Jan-Feb;33(1):32-42.
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Pyrogen release from human synovial exudate cells.人滑膜渗出细胞释放的热原
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Synovial fluid leukocytosis in bacterial arthritis vs. reactive arthritis and rheumatoid arthritis in the adult knee.
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Possible clearance of effete polymorphonuclear leucocytes from synovial fluid by cytophagocytic mononuclear cells: implications for pathogenesis and chronicity in inflammatory arthritis.吞噬性单核细胞可能清除滑膜液中衰老的多形核白细胞:对炎症性关节炎发病机制和慢性化的影响
Ann Rheum Dis. 1993 Feb;52(2):121-6. doi: 10.1136/ard.52.2.121.
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Electron-microscopic investigations on the synovium of the knee joint in rheumatoid arthritis.类风湿性关节炎膝关节滑膜的电子显微镜研究。
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Studies of mononuclear cells from inflammatory joint effusions.炎症性关节积液中单核细胞的研究。
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Granulocyte survival in synovial exudate of patients with rheumatoid arthritis and other inflammatory joint diseases.类风湿关节炎及其他炎性关节疾病患者滑膜渗出液中的粒细胞存活情况。
Yale J Biol Med. 1967 Apr;39(5):289-96.
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Synovial fluid in arthropathy.关节病中的滑液。
Chir Organi Mov. 1991 Jul-Sep;76(3):255-62.

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Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.来自自身免疫性关节炎小鼠的滑液髓样细胞对树突状细胞成熟和T细胞增殖的抑制作用。
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TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin.TSG-6 蛋白是炎症性关节炎的负调控因子,它与鼠肥大细胞类胰蛋白酶和肝素形成三元复合物。
J Biol Chem. 2011 Jul 1;286(26):23559-69. doi: 10.1074/jbc.M111.222026. Epub 2011 May 12.
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Possible clearance of effete polymorphonuclear leucocytes from synovial fluid by cytophagocytic mononuclear cells: implications for pathogenesis and chronicity in inflammatory arthritis.吞噬性单核细胞可能清除滑膜液中衰老的多形核白细胞:对炎症性关节炎发病机制和慢性化的影响
Ann Rheum Dis. 1993 Feb;52(2):121-6. doi: 10.1136/ard.52.2.121.
7
Joint fluid leukocytosis of patients with rheumatoid arthritis evidence for neutrophil and monocyte chemotaxis in vivo.类风湿关节炎患者关节液白细胞增多症:体内中性粒细胞和单核细胞趋化性的证据
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Joint fluid leukocytosis of patient with rheumatoid arthritis Computer analysis of possible explanative factors.类风湿关节炎患者关节液白细胞增多症:可能解释因素的计算机分析
Clin Rheumatol. 1983 Mar;2(1):53-6. doi: 10.1007/BF02032068.