半胱胺：一种有效的特异性垂体催乳素耗竭剂。
Cysteamine: a potent and specific depletor of pituitary prolactin.
作者信息
Millard W J, Sagar S M, Landis D M, Martin J B
出版信息
Science. 1982 Jul 30;217(4558):452-4. doi: 10.1126/science.7089575.
PMID:7089575
Abstract
Cysteamine rapidly reduces the concentration of prolactin in pituitary tissue in vivo and in vitro. The effect is dose-dependent, reversible, and cannot be accounted for by prolactin release. Cysteamine does not appear to exert its effect through dopamine receptors and does not alter lactotrope morphology, as determined by electron microscopy.
摘要
半胱胺能迅速降低体内和体外垂体组织中催乳素的浓度。这种作用具有剂量依赖性、可逆性，且不能用催乳素释放来解释。如通过电子显微镜所确定的，半胱胺似乎不是通过多巴胺受体发挥其作用，也不会改变催乳体细胞的形态。
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