Lifshitz S, Savage J E, Yates S J, Buchsbaum H J
Surg Gynecol Obstet. 1982 Jul;155(1):59-61.
During a 12 year period, 102 patients with invasive epidermoid carcinoma of the vulva were treated at the University of Iowa Hospitals and Clinic. The over-all corrected three year survival rate was 65.5 per cent, or 67 of 102 patients. Those treated by radical vulvectomy and bilateral dissection of groin nodes had a three year survival rate of 76.9 per cent, or 40 of 52 patients, while those treated by radiotherapy had a survival rate of 10 per cent, or two of 20 patients. Those with Stage I disease lesions, less than 1 centimeter in diameter, had an excellent survival rate whether they were treated by vulvectomy only or by radical vulvectomy with groin node dissection. Our experience in this selected group of patients would indicate that a degree of individualization in the treatment of early invasive lesions of the vulva can give most satisfactory results.
在12年期间，爱荷华大学医院及诊所共治疗了102例浸润性外阴表皮样癌患者。总体三年校正生存率为65.5%，即102例患者中的67例。接受根治性外阴切除术及双侧腹股沟淋巴结清扫术的患者三年生存率为76.9%，即52例患者中的40例，而接受放射治疗的患者生存率为10%，即20例患者中的2例。对于直径小于1厘米的I期疾病病变患者，无论仅接受外阴切除术还是接受根治性外阴切除术及腹股沟淋巴结清扫术，其生存率都很高。我们在这组特定患者中的经验表明，对外阴早期浸润性病变进行一定程度的个体化治疗可取得最满意的结果。
