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接受含增塑剂和2-乙基己醇酯类似物饮食的雄性大鼠的血清甘油三酯和胆固醇含量。

Serum triglyceride and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol.

作者信息

Moody D E, Reddy J K

出版信息

Toxicol Lett. 1982 Mar;10(4):379-83. doi: 10.1016/0378-4274(82)90233-8.

DOI:10.1016/0378-4274(82)90233-8
PMID:7089991
Abstract

Male rats were administered diets containing the plasticizers di-(2-ethylhexyl) adipate and di-(ethyl)phthalate,, 2-ethylhexanol, hexanol, 2-ethylhexanoic acid, hexanoic acid, 2-ethylhexyl aldehyde, and hexyl aldehyde for 3 weeks, and serum triglyceride and cholesterol values were determined. Only those compounds which had been found to produce a proliferation of hepatic peroxisomes produced a decrease in both serum lipids.

摘要

给雄性大鼠喂食含有增塑剂己二酸二(2-乙基己基)酯、邻苯二甲酸二乙酯、2-乙基己醇、己醇、2-乙基己酸、己酸、2-乙基己醛和己醛的饲料,持续3周,然后测定血清甘油三酯和胆固醇值。只有那些已被发现会导致肝脏过氧化物酶体增殖的化合物才会使两种血脂都降低。

相似文献

1
Serum triglyceride and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol.接受含增塑剂和2-乙基己醇酯类似物饮食的雄性大鼠的血清甘油三酯和胆固醇含量。
Toxicol Lett. 1982 Mar;10(4):379-83. doi: 10.1016/0378-4274(82)90233-8.
2
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Interactions between plasticizers and fatty acid metabolism in the perfused rat liver and in vivo. Inhibition of ketogenesis by 2-ethylhexanol.灌注大鼠肝脏及体内增塑剂与脂肪酸代谢的相互作用。2-乙基己醇对生酮作用的抑制。
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Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis.增塑剂己二酸二(2-乙基己基)酯(己二酸二辛酯,DOA)对大鼠脂质代谢的影响:I. 抑制胆固醇生成及改变磷脂合成
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Peroxisome proliferation due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid.己二酸二(2-乙基己基)酯、2-乙基己醇和2-乙基己酸导致过氧化物酶体增殖。
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Peroxisome induction studies on di(2-ethylhexyl)terephthalate.对二(2-乙基己基)对苯二甲酸酯的过氧化物酶体诱导研究。
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Bacterial mutagenicity testing of urine from rats dosed with 2-ethylhexanol derived plasticizers.
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