Sastry K V, Tyagi S
Toxicol Lett. 1982 Apr;11(1-2):17-21. doi: 10.1016/0378-4274(82)90099-6.
The effect of in vivo exposure to a sublethal concentration of hexavalent chromium for 30 days on blood glucose, blood liver and muscle lactic acid; haemoglobin, liver and muscle glycogen; and activities of lactate dehydrogenase (LDH), pyruvate dehydrogenase (PHD) and succinate dehydrogenase (SDH) in liver, muscle, kidney, gills and brain has been studied. Blood glucose and lactic acid levels were elevated. Liver glycogen was depleted but muscle glycogen content increase. The activities of LDH and SDH in liver were elevate. Elevation was also observed in muscle LDH and PDH activities, showing that the rate of glycolysis is increased. No change was noted in haemoglobin content of blood or in the activities of the three dehydrogenases in kidney and gills.
研究了在体内暴露于亚致死浓度的六价铬30天对血糖、血肝和肌肉乳酸;血红蛋白、肝和肌肉糖原;以及肝脏、肌肉、肾脏、鳃和大脑中乳酸脱氢酶(LDH)、丙酮酸脱氢酶(PHD)和琥珀酸脱氢酶(SDH)活性的影响。血糖和乳酸水平升高。肝糖原耗尽,但肌肉糖原含量增加。肝脏中LDH和SDH的活性升高。肌肉中LDH和PDH的活性也升高,表明糖酵解速率增加。血液中血红蛋白含量以及肾脏和鳃中三种脱氢酶的活性均未观察到变化。