[Spontaneous blood serum chemiluminescence in detecting recurrences and metastases of cancer of the proximal portion of the stomach and esophagus].

The report deals with the results of examination of 48 healthy donors and 261 patients suffering from malignant tumors of cardia and esophagus, 84 patients after radical surgery included. Spontaneous chemoluminescence (CL) of blood serum was shown to depend on the general condition of the patient and tumor involvement before treatment: there is a direct correlation between these factors and luminescence intensity. Therefore, CL may be used as a laboratory test providing necessary information for developing treatment modality for each individual case. Within 0.5-60 months after radical treatment, the rise in the intensity of blood serum CL (60-100% and more) was registered in cases of pyo-inflammatory complications (peritonitis, mediastinitis, pleural empyema, etc.) and recurrence and metastatic spreading. A rise in CL intensity by more than 50% and a steady tendency to further increase may be interpreted as a pointer to recurrence or metastasis development.