Smulevich A B, Orlova V A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(4):85-91.
Post-treatment examinations of 210 patients with stable and long-lasting paranoia states who had been treated both as in- and outpatients at the Institute of Psychiatry, the USSR Academy of Medical Sciences, in 1960 to 1966, have made it possible to differentiate 9 cases which corresponded in their clinical features to Kraepelin's paranoia. The long-term (for 14 to 20 years) catamnestic examinations showed that only in 2 patients signs of a slowly progressing schizophrenic process could be observed. In all other cases no signs of the progress of the negative changes were registered. Moreover, 5 patients showed a gradual reduction of the delusional disturbances. Data on hereditary aggravation are presented, and rightfulness of grouping paranoia with diseases of the schizophrenic spectrum is discussed. The results of the study point out that attempts at abolishing the problem of paranoia are premature.
对1960年至1966年期间在苏联医学科学院精神病学研究所接受门诊和住院治疗的210例处于稳定且持久偏执状态的患者进行治疗后检查，得以区分出9例临床特征与克雷佩林偏执症相符的病例。长期（14至20年）的随访检查表明，仅在2例患者中观察到缓慢进展的精神分裂症过程迹象。在所有其他病例中，均未记录到负面变化进展的迹象。此外，5例患者的妄想障碍逐渐减轻。文中呈现了遗传易感性数据，并讨论了将偏执症与精神分裂症谱系疾病归为一组的合理性。研究结果指出，试图消除偏执症问题的做法为时过早。
