孕中期羊水穿刺术血液污染的临床意义。

The clinical significance of blood-contaminated midtrimester amniocentesis.

作者信息

Ron M, Cohen T, Yaffe H, Beyth Y

出版信息

Acta Obstet Gynecol Scand. 1982;61(1):43-5. doi: 10.3109/00016348209156950.

DOI:10.3109/00016348209156950

Abstract

In 706 midtrimester amniocenteses, 180 (25.5%) samples yielded blood-stained amniotic fluid (macroscopically and microscopically), 152 (21.5%) contained maternal blood, 28 (3.9%) fetal blood and 8 samples contained both maternal and fetal blood. In the 180 cases of bloody midtrimester amniocentesis, the abortion rate was 6.6% when maternal blood was found and 14.3% when fetal blood was aspirated, compared with 1.7% in controls. The amount of blood drawn did not alter pregnancy outcome. The percentage of blood amniotic fluid in amniocenteses performed before the 16th week of pregnancy was much higher (36.7%) than during and after the 16th week of pregnancy (22%). Midtrimester amniocentesis should therefore be avoided before the 16th week of pregnancy.

摘要

在706例孕中期羊膜腔穿刺术中，180例（25.5%）样本产生了血性羊水（肉眼和显微镜下观察），152例（21.5%）含有母血，28例（3.9%）含有胎儿血，8例样本同时含有母血和胎儿血。在180例孕中期血性羊膜腔穿刺术中，发现母血时流产率为6.6%，抽取到胎儿血时流产率为14.3%，而对照组为1.7%。抽取的血量并未改变妊娠结局。妊娠16周前进行羊膜腔穿刺术时血性羊水的比例（36.7%）远高于妊娠16周期间及之后（22%）。因此，孕16周前应避免进行孕中期羊膜腔穿刺术。