Reitamo J J, Häyry P, Nykyri E, Saxén E
Am J Clin Pathol. 1982 Jun;77(6):665-73. doi: 10.1093/ajcp/77.6.665.
We have (1) estimated the incidence of desmoid tumor (DT) in the Finnish population, and (2) defined statistically four major age components of the DT with different biological properties. The incidence of the DT, based on admissions to four separate hospitals and on the number of pathological biopsy specimens analyzed at the Central Pathological Laboratory of Helsinki University, is 2.4-4.3 new cases per 10(6) inhabitants per annum. Statistical analysis demonstrated four major age components where the site of the tumor and/or sex of the patient were non-randomly distributed: "juvenile" DT, a predominantly extra-abdominal desmoid tumor of the female sex; "fertile" DT, a nearly exclusively abdominal DT of fertile females; "menopausal" DT, a predominantly abdominal tumor where the sex ratio approaches one:one; and "senescent" DT, where abdominal and extra-abdominal varieties are equally frequently encountered and where the sex ratio of the affected patients is one:one.
我们（1）估算了芬兰人群中硬纤维瘤（DT）的发病率，并且（2）从统计学角度定义了具有不同生物学特性的DT的四个主要年龄组分。基于四家独立医院的入院人数以及赫尔辛基大学中央病理实验室分析的病理活检标本数量，DT的发病率为每年每10^6居民中有2.4 - 4.3例新发病例。统计分析显示了四个主要年龄组分，肿瘤部位和/或患者性别在这些组分中呈非随机分布：“青少年型”DT，主要为女性的腹外硬纤维瘤；“育龄型”DT，几乎仅见于育龄女性的腹部DT；“绝经型”DT，主要为腹部肿瘤，其性别比接近1:1；以及“老年型”DT，腹部和腹外类型出现频率相同，且受累患者的性别比为1:1。
