采用血浆置换治疗血液透析相关迟发性皮肤卟啉病。

Treatment of hemodialysis-related porphyria cutanea tarda with plasma exchange.

作者信息

Disler P, Day R, Burman N, Blekkenhorst G, Eales L

出版信息

Am J Med. 1982 Jun;72(6):989-93. doi: 10.1016/0002-9343(82)90860-9.

Abstract

A patient with hemodialysis-related porphyria cutanea tarda was treated with plasma exchange. A rapid clinical response occurred coincidentally with a significant fall in the plasma porphyrin level. The level fell further over the following few months without additional therapeutic intervention, whereafter a slow rise occurred without recurrence of skin disease. We suggest that this form of treatment may be ideal for the patient with porphyria cutanea tarda and chronic renal failure in whom no alternative therapy is available for the cutaneous problem.

摘要

一名患有血液透析相关迟发性皮肤卟啉症的患者接受了血浆置换治疗。临床症状迅速缓解，同时血浆卟啉水平显著下降。在接下来的几个月里，即使没有额外的治疗干预，卟啉水平仍进一步下降，此后虽缓慢上升，但皮肤病未复发。我们认为，对于患有迟发性皮肤卟啉症和慢性肾衰竭且皮肤问题没有其他替代疗法的患者，这种治疗方式可能是理想的。