Morimoto K, Okamura H, Tanaka C
Am J Obstet Gynecol. 1982 Jun 15;143(4):389-92. doi: 10.1016/0002-9378(82)90078-3.
Norepinephrine (NE) and dopamine (DA) contained in the rat ovary were determined by high-performance liquid chromatography with electrochemical detection. Concentration of ovarian NE reached adult levels around 5 weeks of age, when the first ovulation occurs. During induction of ovulation, the ovarian NE contents increased slightly during the preovulatory phase, followed by a significant decrease in the postovulatory phase, whereas the turnover of ovarian NE decreased during the preovulatory phase. These results suggest that ovarian noradrenergic nerves were in a somewhat inactivated state during the preovulatory phase. Therefore, ovarian sympathetic nerves are considered to participate in mechanisms of the onset of puberty and ovulation.
采用高效液相色谱-电化学检测法测定大鼠卵巢中的去甲肾上腺素(NE)和多巴胺(DA)。卵巢NE浓度在约5周龄时达到成年水平,此时首次排卵发生。在诱导排卵过程中,卵巢NE含量在排卵前期略有增加,随后在排卵后期显著下降,而卵巢NE的周转率在排卵前期下降。这些结果表明,卵巢去甲肾上腺素能神经在排卵前期处于某种失活状态。因此,卵巢交感神经被认为参与青春期启动和排卵机制。