Smith E R, Dresel P E
Anesthesiology. 1982 Aug;57(2):98-102. doi: 10.1097/00000542-198208000-00006.
A constantly coupled bigeminal arrhythmia was induced in dogs anesthetized with thiopental-halothane by infusion of epinephrine (1 microgram.kg-1.min-1). The site of origin of the abnormal beat was localized to the interventricular septum by bipolar recordings from the left and right ventricular epicardium and two sites in the septum. Simultaneous echocardiograms showed early movement of the septum with a pattern similar to that seen in the left bundle branch block. Simulation at the recording sites resulted in movement patterns which indicate that assessment of septal and posterior left ventricular motion can be helpful in localization of the origin of ventricular arrhythmias, although only with left ventricular arrhythmias is there potential for anatomic localization to a small area of muscle.
通过输注肾上腺素（1微克·千克⁻¹·分钟⁻¹），在硫喷妥钠-氟烷麻醉的犬中诱发持续联律性二联律心律失常。通过从左、右心室心外膜以及室间隔的两个部位进行双极记录，将异常搏动的起源部位定位到室间隔。同步超声心动图显示室间隔早期运动，其模式类似于左束支传导阻滞所见。在记录部位进行模拟产生的运动模式表明，评估室间隔和左心室后壁运动有助于定位室性心律失常的起源，尽管只有左心室心律失常有可能在解剖学上定位到一小片肌肉区域。
