Westerhof W
Acta Derm Venereol. 1977;57(4):297-304.
An E.M. study was carried out to investigate whether Mycobacterium leprae occur intracellularly in epidermal melanocytes. As this could not be confirmed, the selective killing of melanocytes by cytotoxic lymphocytes could not explain the hypopigmentation in types of leprosy with a relative good immune response. There were indications that these hypopigmented lesions resulted from a disturbed transfer of melanosomes from melanocytes to keratinocytes. Further research is in progress.
进行了一项电子显微镜研究，以调查麻风分枝杆菌是否在表皮黑素细胞内出现。由于这一点无法得到证实，细胞毒性淋巴细胞对黑素细胞的选择性杀伤无法解释免疫反应相对良好的麻风类型中的色素减退现象。有迹象表明，这些色素减退性病变是由于黑素小体从黑素细胞向角质形成细胞的转运紊乱所致。进一步的研究正在进行中。
