早产儿佝偻病中的血浆碱性磷酸酶活性
Plasma alkaline phosphatase activity in rickets of prematurity.
作者信息
Glass E J, Hume R, Hendry G M, Strange R C, Forfar J O
出版信息
Arch Dis Child. 1982 May;57(5):373-6. doi: 10.1136/adc.57.5.373.
Abstract
Plasma alkaline phosphatase activity was measured in 349 infants aged between 5 and 10 days to establish a normal range for different gestational ages. Significant differences were observed between term and preterm infants, the highest values being associated with the shortest lengths of gestation. Plasma calcium, phosphate, and alkaline phosphatase activity were measured sequentially in 51 preterm infants less than 1500 g at birth. A significant correlation was found between raised plasma alkaline phosphatase activity and radiological changes of osteoporosis, metaphyseal change, and periosteal reaction. Plasma alkaline phosphatase appears to be of value in screening for and monitoring rickets of prematurity.
摘要
测量了349名5至10日龄婴儿的血浆碱性磷酸酶活性，以确定不同胎龄的正常范围。足月儿和早产儿之间观察到显著差异，值最高者与最短的妊娠期相关。对51名出生时体重不足1500g的早产儿依次测量了血浆钙、磷和碱性磷酸酶活性。发现血浆碱性磷酸酶活性升高与骨质疏松、干骺端改变和骨膜反应的放射学改变之间存在显著相关性。血浆碱性磷酸酶似乎在筛查和监测早产儿佝偻病方面具有价值。
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