Streeten B W
Arch Ophthalmol. 1982 Jun;100(6):969-75. doi: 10.1001/archopht.1982.01030030977016.
Ultrastructural studies were performed on five cases of asteroid hyalosis of the human vitreous. The large asteroid bodies were composed if intertwined ribbons of multilaminar membranes with a 6-nm periodicity characteristic of complex lipids, especially phospholipids, lying in a homogeneous background matrix. Clumps of dense material were interspersed throughout the asteroids, and swirls of thin membranous strands often surrounded them. The structure of small asteroid bodies suggested that the lipid ribbons resulted from deposition of successive lipid layers on the thin membranes, so that bodies with variable degrees of lipidization occur. By energy-dispersive x-ray analysis, calcium and phosphorus were the main elements detectable in asteroid bodies of all sizes. Electron-diffraction structural analysis showed that calcium hydroxyapatite and, possibly, other forms of calcium phosphate crystals were present in the focal densities. Calcium may also be bound to phosphate groups in the phospholipids. The large quantity of complex lipids and calcium in asteroids bodies suggests a derivation from sources exogenous to the vitreous.
对5例人类玻璃体星状玻璃体变性进行了超微结构研究。大的星状体由多层膜交织而成的条带组成，具有6纳米的周期性，这是复合脂质特别是磷脂的特征，位于均匀的背景基质中。致密物质团块散布于整个星状体内，细膜状条带的漩涡常常环绕着它们。小行星状体的结构表明，脂质条带是由连续的脂质层沉积在薄膜上形成的，因此会出现不同程度脂质化的星体。通过能量色散X射线分析，钙和磷是所有大小星状体内可检测到的主要元素。电子衍射结构分析表明，羟基磷灰石钙以及可能的其他形式的磷酸钙晶体存在于局灶性致密区。钙也可能与磷脂中的磷酸基团结合。星状体内大量的复合脂质和钙表明其来源于玻璃体外部。
