Herxheimer A, Lionel N D
Br Med J. 1978 Oct 21;2(6145):1129-32. doi: 10.1136/bmj.2.6145.1129.
The prescriber needs adequate and concise information about each product that he uses, to allow him to obtain optimal effects while minimising harm. Neither the present UK data sheets nor their equivalents in other countries have succeeded in providing such information clearly or completely. This paper develops the proposals on the arrangement of drug information made in the WHO report "The selection of essential drugs." Three sets of minimum information (on tetracycline, propranolol, and aspirin) which illustrate this approach were compared with the manufacturers' data sheets: the latter were incomplete. The information content of our proposals was worked out with a group of clinical pharmacologists, general practitioners, and specialists, and we suggest that this approach should be extended to other drugs.
开处方者需要有关其所使用的每种药品的充分且简洁的信息，以便在将危害降至最低的同时获得最佳效果。无论是目前英国的药品说明书，还是其他国家的同类说明书，都未能清晰或完整地提供此类信息。本文拓展了世界卫生组织报告《基本药物的选择》中关于药物信息编排的提议。将说明该方法的三组最低限度信息（关于四环素、普萘洛尔和阿司匹林）与制造商的药品说明书进行了比较：结果发现后者并不完整。我们与一组临床药理学家、全科医生和专家共同确定了我们提议中的信息内容，并且我们建议应将这种方法推广至其他药物。
