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[遗传因素在儿童和青少年动脉血压升高产生中的作用(青少年动脉高血压国际合作研究)]

[Role of hereditary factors in producing elevated arterial pressure in children with adolescents (International Cooperative Study on Juvenile Arterial Hypertension)].

作者信息

Aleksandrov A A, Glazunov I S, Antonova L T, Nadezhdina E A, Boiarskas Iu

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1982;5(1):26-30.

PMID:7093042
Abstract

In 1977 in the cooperating centres (Moscow, Budapest, Berlin, Habana) 17,628 schoolchildren born in 1964, were examined, and a group was distinguished with increased BP (1862 children) and 10% random samples of the examined schoolchildren with normal BP. All the parents of the examined schoolchildren, including grandparents, were mailed questionnaire which concerned the family anamnesis, in particular, cases of cardiovascular diseases. The mailed questionnaires were answered by 74% of parents which permits one to judge about a high authenticity of the obtained results. The analysis of the results obtained by that questionnaire affirmed a higher incidence of cardiovascular diseases found in relatives of the children with increased BP than in relatives of the children with normal BP.

摘要

1977年,在合作中心(莫斯科、布达佩斯、柏林、哈瓦那)对1964年出生的17628名学童进行了检查,区分出血压升高组(1862名儿童)以及血压正常的被检查学童的10%随机样本。向所有被检查学童的父母,包括祖父母,邮寄了涉及家族病史,尤其是心血管疾病病例的问卷。74%的父母回复了邮寄的问卷,这使得人们能够判断所获结果具有较高的可信度。对通过该问卷获得的结果进行分析后确认,血压升高儿童亲属中发现的心血管疾病发病率高于血压正常儿童的亲属。

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