Riemersma R A, Logan R, Russell D C, Smith H J, Simpson J, Oliver M F
Br Heart J. 1982 Aug;48(2):134-9. doi: 10.1136/hrt.48.2.134.
Free fatty acid concentrations in plasma measured after in vivo heparinisation are often overestimated because of ex vivo lipolysis of variable degrees. A new method has been developed using immediate extraction of blood which obviates this and shows that the true rise in plasma free fatty acid concentration after heparin in ambulant ward patients and in patients with acute myocardial infarction is less than previously reported. The small rise in plasma free fatty acid concentration after heparin is unlikely to have adverse metabolic effects in most patients during acute myocardial infarction.
体内肝素化后所测得的血浆游离脂肪酸浓度常因离体后不同程度的脂解作用而被高估。一种新方法已被开发出来，即通过立即采血来避免这种情况，该方法表明，在普通病房患者和急性心肌梗死患者中，肝素化后血浆游离脂肪酸浓度的实际升高幅度小于先前报道。肝素化后血浆游离脂肪酸浓度的小幅升高在大多数急性心肌梗死患者中不太可能产生不良代谢影响。
