醋酸铀酰对人淋巴母细胞（RPMI 6410）和HeLa细胞的作用。

Ghadially F N, Yang-Steppuhn S E, Lalonde J M

Br J Exp Pathol. 1982 Jun;63(3):227-34.

RPMI 6410 cells and HeLa cells were exposed to uranyl acetate. In RPMI 6410 cell cultures this produced single-membrane-bound presumably lysosomal bodies (called "uraniosomes") containing electron-dense crystals in the cultured cells and crystalline deposits in extracellular locations. Neither uraniosomes nor extracellular uranium deposits were found in HeLa cell cultures. All uraniosomes and extracellular uranium deposits analysed by electron-probed X-ray analysis were found to contain uranium, potassium and phosphorus. Traces of sulphur were detected in some but not all uraniosomes and extracellular uranium deposits. Traces of calcium were found in all extracellular uranium deposits and in some uraniosomes also.

将RPMI 6410细胞和HeLa细胞暴露于醋酸铀中。在RPMI 6410细胞培养物中，这在培养细胞中产生了单膜结合的、可能是溶酶体的小体（称为“铀体”），其中含有电子致密晶体，在细胞外位置有晶体沉积物。在HeLa细胞培养物中未发现铀体和细胞外铀沉积物。通过电子探针X射线分析的所有铀体和细胞外铀沉积物均发现含有铀、钾和磷。在一些但不是所有的铀体和细胞外铀沉积物中检测到微量硫。在所有细胞外铀沉积物中以及一些铀体中也发现了微量钙。