钠对突触体去极化诱导的钙摄取和乙酰胆碱释放的影响。
The effect of sodium on depolarization-induced calcium uptake and acetylcholine release by synaptosomes.
作者信息
Metlas R, Nikezić G
出版信息
Biochim Biophys Acta. 1982 May 7;687(2):340-2. doi: 10.1016/0005-2736(82)90566-1.
PMID:7093264
Abstract
The influence of external sodium concentration on potassium (depolarizing agent)-stimulated calcium uptake and Ca+-dependent acetylcholine release by rat cerebral cortex synaptosomes has been studied. It was found that increased sodium concentration decreased both the Ca2+ uptake and the acetylcholine release, whereas a low external sodium concentration is stimulatory.
摘要
研究了细胞外钠浓度对大鼠大脑皮层突触体中钾（去极化剂）刺激的钙摄取以及钙依赖性乙酰胆碱释放的影响。结果发现，钠浓度升高会降低钙摄取和乙酰胆碱释放，而低细胞外钠浓度则具有刺激作用。
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