Ghiselli G
Biochim Biophys Acta. 1982 May 13;711(2):311-5. doi: 10.1016/0005-2760(82)90040-6.
The plasma specific activity of apolipoprotein B was determined in normal rabbit injected with homologous radioiodinated very low and intermediate density lipoproteins (VLDL and IDL). The specific activity was followed in the same density range of the injected lipoproteins and in two low density lipoprotein subfractions (LDL1 and LDL2). VLDL B (d less than 1.006 g/ml) is cleared from plasma mainly in IDL (d = 1.006-1.019 g/ml), with minor radioactivity recovery in LDL1 (d = 1.019-1.040 g/ml) and LDL2 (d = 1.040-1.063 g/ml) fractions. The main catabolic product of IDL B is, on the other hand, LDL1 B. LDL2 B, which represent more than 20% of the whole LDL B plasma pool in this animal species, is not derived to a significant extent from either VLDL or IDL and, conceivably, is synthesized independently.
在注射了同源放射性碘标记的极低密度脂蛋白和中间密度脂蛋白（VLDL和IDL）的正常兔子中，测定了载脂蛋白B的血浆比活性。在注射脂蛋白的相同密度范围内以及两个低密度脂蛋白亚组分（LDL1和LDL2）中跟踪比活性。VLDL B（d小于1.006 g/ml）主要在IDL（d = 1.006 - 1.019 g/ml）中从血浆中清除，在LDL1（d = 1.019 - 1.040 g/ml）和LDL2（d = 1.040 - 1.063 g/ml）组分中的放射性回收较少。另一方面，IDL B的主要分解代谢产物是LDL1 B。LDL2 B在该动物物种中占整个LDL B血浆池的20%以上，在很大程度上不是来自VLDL或IDL，并且可以想象是独立合成的。
