Grenader A K, Zurabishvili G G
Biofizika. 1982 May-Jun;27(3):505-8.
Ectopic spiral wave sources--reverberators--were produced in pieces of rabbit atrium and ventricle by an induction of a single properly timed premature impulse. It was found that the cycle length (T) of the ectopic source gradually increased immediately after its appearance in atrial and changed a little bit after its appearance in ventricular tissue. Relationship between changes of T and refractorines of the heart tissues was investigated. The model is proposed which explains these changes of T by the cycle length dependence on the value of fast inward sodium current.
异位螺旋波源——折返器——是通过适时诱发单个过早冲动在兔心房和心室组织片中产生的。研究发现,异位源的周期长度(T)在出现在心房组织后立即逐渐增加,而在出现在心室组织后变化较小。研究了T的变化与心脏组织不应期之间的关系。提出了一个模型,该模型通过周期长度对快速内向钠电流值的依赖性来解释T的这些变化。