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晶状体纤维细胞之间连接的结构。

The structure of junctions between lens fiber cells.

作者信息

Simon S A, Zampighi G, McIntosh T J, Costello M J, Ting-beall H P, Robertson J D

出版信息

Biosci Rep. 1982 May;2(5):333-41. doi: 10.1007/BF01115119.

Abstract

Junctions which have been isolated from bovine lens may correspond to the tongue-and groove interdigitations observed between intact cells. These junctions have an overall thickness of 13-14 nm, a striking undulating surface topology, and contain protein subunits of congruent to 27 000 daltons which are arranged in a 6.6-6.7-nm square lattice in the plane of each membrane. A similar square-lattice structure has been observed in junctions from fragments of intact rate lens. Junctions from both sources are structurally different from "typical' gap junctions.

摘要

从牛晶状体中分离出的连接可能与完整细胞间观察到的舌槽状交错连接相对应。这些连接的总厚度为13 - 14纳米,具有显著的起伏表面拓扑结构,并且包含与27000道尔顿相当的蛋白质亚基,这些亚基在每个膜平面中以6.6 - 6.7纳米的正方形晶格排列。在完整大鼠晶状体碎片的连接中也观察到了类似的正方形晶格结构。来自这两种来源的连接在结构上与“典型的”间隙连接不同。

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