Singh M, Vatsala T M
Biorheology. 1982;19(1/2):165-73. doi: 10.3233/bir-1982-191-219.
The erythrocyte sedimentation profiles under gravitational field, by scanning the sample holder along the height and width, containing the blood samples with normal and crenated erythrocytes, are determined. The normal shape of erythrocytes has been altered by the controlled He-Ne laser exposures and this change, as observed microscopically, is similar to that as produced by other methods. At low exposure the erythrocytes have normal appearance, whereas, at 400 mJ/cm2, the percentage of crenated cells is 25 +/- 5 percent. It is observed that the modification of the shape influences the sedimentation characteristics of the erythrocytes. The erythrocytes tend to move faster after being exposed to lower exposure and slower after being exposed to higher exposure compared to that of normal erythrocytes. The possible mechanism associated with this change is discussed.
通过沿高度和宽度扫描包含正常红细胞和皱缩红细胞血样的样品架,测定了重力场下的红细胞沉降曲线。通过可控的氦氖激光照射改变了红细胞的正常形状,显微镜观察到的这种变化与其他方法产生的变化相似。在低照射量下,红细胞外观正常,而在400 mJ/cm²时,皱缩细胞的百分比为25±5%。观察到形状的改变会影响红细胞的沉降特性。与正常红细胞相比,红细胞在低照射量下暴露后移动得更快,在高照射量下暴露后移动得更慢。讨论了与这种变化相关的可能机制。